DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE bronic ester 184 SMILES [2H]C([2H])([2H])OC1=CC=C(CO)C=C1 Purity (HPLC)

184 SMILES [2H]C([2H])([2H])OC1=CC=C(CO)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Mal-Propionyl-PEG4-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C98H153N13O30 Molecular Weight 1993

S)-AHPC-CO-C5-NH2 HCl Synonyms CAS Number 2415256-20-9 Related CAS 2170695-19-7 (free base) Molecular Formula C28H43Cl2N5O4S Molecular Weight 616

Product Name methyl 2-[4-(d3-methoxyphenyl]acetate Synonyms CAS Number n/a Related CAS Molecular Formula C10H12O3 Molecular Weight 183

NCCOCCOCCOCCOCCOCCNC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE bronic ester 184 SMILES [2H]C([2H])([2H])OC1=CC=C(CO)C=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to